Zebra ZD621 Healthcare
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ZD621 Healthcare Barcode Printers
ZD621 Healthcare
Invest in the best: premium features, maximum performance and unmatched security for years of quality printing
The Zebra ZD621 Healthcare gives clinical, lab and pharmacy teams a compact premium printer built for consistent desktop labeling in demanding healthcare workflows. It brings the ZD600 Series architecture, strong print performance and Zebra DNA software tools into a healthcare configuration designed for cleaner handling and easier day-to-day use.
This model is made for patient identification, specimen collection, prescription labeling, lab management and asset labeling. Standard Ethernet, USB 2.0 and USB host connectivity help it fit into existing workstations, while optional wireless and media-handling choices let the printer grow with changing requirements.
Your Future Printing Starts Here
Technology for Today, Innovation for Tomorrow
ZD600 Series printers are designed around an architecture that can support expanding printer features and software over time. The ZD621 Healthcare can be configured with current wireless options, including Wi-Fi 6/6E support with Bluetooth® 5.3, to align with modern healthcare network upgrades.
Expect the Best
Premium Printing Performance
Premium desktop printing helps teams keep pace at registration desks, nursing stations, labs and pharmacies. The ZD621 Healthcare supports direct thermal and thermal transfer workflows, optional 300 dpi resolution and flexible media support for common healthcare labels and wristbands.
Simple to Setup, Easy to Maintain
Operate with Ease, Securely
Zebra DNA tools help simplify deployment, setup and remote management. Status icons, setup utilities and the standard healthcare touch LCD make printer status and configuration easier to handle with minimal training.
Premium Features, Small Footprint
Load Media Easily
OpenACCESS™ media loading and color-coded touch points help staff replace media quickly. Thermal transfer configurations also support intuitive ribbon replacement to reduce interruptions during busy clinical shifts.
Engineered for Outstanding Print Quality
The ZD621 offers 203 dpi standard resolution, with 300 dpi available when smaller text, dense barcodes or compact labels need added detail. Thermal transfer models include Zebra print-quality features designed to keep labels and tags consistent across print speeds.
See Printer Status in Color and Change Settings with a Touch
The 4.3-inch full-color touch LCD is standard on healthcare models, giving users clear access to printer status, setup menus and guided printer functions. This helps reduce training time and makes common adjustments easier at the point of use.
Hassle-Free Integration
Backwards Compatible with Virtually Any Existing Thermal Printer
Support for ZPL and EPL makes it easier to place the ZD621 Healthcare into existing label environments. Zebra DNA Printer Emulations can also help organizations preserve legacy label formats and applications during printer fleet transitions.
Comprehensive Communication to Connect Your Way
Ethernet, USB 2.0, USB host and serial connectivity are standard on the ZD621. Optional dual wireless radio configurations support Wi-Fi and Bluetooth connections, and NFC Print Touch helps simplify pairing and access to support resources.
Innovative Features that Work for You
Add Mobility for On-the-spot Printing
An optional battery can power the printer through mobile workflows, helping teams print labels closer to the work instead of returning to a fixed workstation. This can reduce extra steps and support more accurate labeling at the point of care.
Moveable Sensor Means More Flexibility
A full-width moveable reflective/black mark sensor and a multi-position transmissive/gap sensor help the printer handle a wide range of roll-fed and fan-fold media, including labels, tag stock, receipt paper and supported wristbands.
Zebra DNA for Printers
Confident and Secure Printing, Without the Hassle
Zebra DNA, powered by Link-OS™, supports setup, secure operation, management and optimization across the printer lifecycle. These tools help keep healthcare printing dependable as workflows and security expectations evolve.
Update, Troubleshoot and Monitor, All from a Single Location
Printer Profile Manager Enterprise gives administrators a way to manage, secure and troubleshoot networked Zebra DNA printers remotely, helping reduce hands-on printer maintenance across larger facilities.
Unmatched Printing Security
PrintSecure, part of Zebra DNA, helps administrators strengthen printer security by supporting secure configuration, identifying vulnerabilities and limiting unauthorized access across connected printer environments.
Supplies, Service and Support
Zebra Certified Supplies
Zebra Certified Supplies are designed and tested to deliver consistent, optimized performance in Zebra printers. For healthcare workflows, the right labels, wristbands and receipt media help preserve readability and reduce disruptions tied to poor supplies performance.
Backed by Zebra's Worldwide Service and Support
Zebra service and support options help organizations keep printers in service across distributed clinical environments. Zebra OneCare™ maintenance plans provide enhanced support options that go beyond standard warranty coverage.
Healthcare Applications
The ZD621 Healthcare supports common healthcare workflows including specimen collection, prescription labeling, lab management, patient ID wristbands, asset labels and patient records.
Key Specifications
The ZD621 supports thermal transfer or direct thermal printing, 203 dpi standard resolution, optional 300 dpi resolution, 512 MB Flash memory and 256 MB SDRAM. The maximum print width is 4.09 inches at 203 dpi and 4.27 inches at 300 dpi, with print speeds up to 8 inches per second at 203 dpi and 6 inches per second at 300 dpi.
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| Media Width |
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| Media Roll Size |
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| Media Thickness | 0.003 in. (0.08 mm) min.; 0.0075 in. (0.19 mm) max. (tear-off mode only) |
| Media Types | Roll-fed or fan-fold, die cut or continuous with or without black mark, label or tag stock, continuous receipt paper, wristbands |
| Ribbon Outside Diameter | 2.6 in./66 mm (300 m); 1.34 in./34 mm (74 m) |
| Ribbon Standard Length | 984 ft. (300 m); 243 ft. (74 m) |
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| Ribbon Width | 1.33 in./33.8 mm — 4.3 in./109.2 mm |
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| Operating Temp. | 40° to 105° F/4.4° to 41° C |
| Operating Humidity | 10% to 90% non-condensing |
| Storage Humidity | 5% to 95% non-condensing |
| Electrical | Auto-detectable (PFC Compliant) 100-240VAC, 50-60Hz; ENERGY STAR certified; Energy Efficiency Level VI certified; optional 2750 mAh battery; Healthcare models include IEC60601-1 certified power supply |
| Media Handling | Dispenser/Peeler: label peel and present with label present sensor (factory installed or field installable) Cutter (factory installed or field installable) |
| Communications | 802.11ac Wi-Fi and Bluetooth 4.1 (dual radio), (factory installed or field installable) |
| Battery | Provides power to the printer to support a full shift of printing at maximum print speed; supports all connectivity and media handling options |
| Carrying Case | Carrying case with shoulder strap and handles makes it easy to bring your desktop printer and battery to the point of application |
| Keyboard Display Unit | Zebra Keyboard Display Unit (ZKDU) for stand- alone printing solutions |
| Media Locking Cabinet | Mechanical lock with 2 keys; Kensington™ lock slot; available on ZD621 healthcare direct thermal model only |
| Enclosed Power Supply | Attached power supply accessory for cord-free installation |
| Bar Code Ratios | 2:1 and 3:1 |
| 1D Bar Codes | Code 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A, UPC-E, EAN-8, EAN-13, UPC and EAN 2-or 5-digit extensions, Plessey, Postnet, Standard 2-of- 5, Industrial 2-of-5, Interleaved 2-of-5, Logmars, MSI, Codabar and Planet Code |
| 2D Bar Codes | Codablock, PDF417, Code 49, DataMatrix, MaxiCode, QR Code, MicroPDF, Aztec |
| Fonts and Graphics | 16 resident expandable ZPL II bitmap fonts, two resident scalable ZPL fonts, five resident expandable EPL2 fonts, native open-type font support, Unicode compliant. China units include SimSun simplified Chinese font |
| Printers Supplies | For industry-leading quality, service and thermal printing expertise, choose Zebra Certified Supplies to ensure consistent, optimized performance for your Zebra printer. |
| Environment | • RoHS Directive 2011/65/EU; Amendment 2015/863 A complete list of product and materials compliance, please visit www.zebra.com/environment |
| Included In The Box | Printer, empty ribbon take-up cores (1 in. and 0.5 in.)*, 300 m ribbon core adapters for non-Zebra ribbon (2)*, AC power supply, power cord(s), USB cable, Quick Start Guide, Regulatory Guide * Empty ribbon take-up cores and ribbon core adapters included with ZD621 thermal transfer models only |
| Product Warranty | ZD600 Series printers are warranted against defects in workmanship and materials for a minimum period of 2 (two) years from the date of shipment. Warranty varies by region. For complete warranty details, please visit www.zebra.com/warranty |
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